Progynon Depot-Estradiol Valerate 10mg/1ml

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Progynon Depot-Estradiol Valerate 10mg/1ml

Progynon Depot is an efficacious therapy for the treatment of postmenopausal symptoms in adults. Progynon Depot is a hormone replacement therapy (HRT) used by women to treat the postmenopausal symptoms such as flushing, palpitations, sweating, sleeplessness and vaginal dryness by enhancing the levels of certain hormones such as Estradiol in the body. Progynon Depot replenishes the lack of estrogen production in the body that occurs during the menopause or even when there is a surgical removal of ovaries.  Apart from being an HRT, Progynon is widely employed to treat postmenopausal osteoporosis in elderly women.  

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How does Progynon Depot 10mg/1ml work?

Progynon Depot comprises of Oestradiol Valerate as the main functional moiety. Progynon is the synthetic form of naturally occurring Oestradiol, which is the active form of the female sex hormone called estrogen. Progynon Depot acts as a substitute for the estrogen deficiency occurring in menopause. This is responsible for the occurrence of hot flashes, mood swings, and vaginal dryness. Estrogen also has quite a few other events in various metabolic processes including preserving bone mass and lipid (fat) metabolism. 

What is the dosing method for Progynon depot 10mg/1ml?

Progynon Depot is commercially available in a dosing strength of 10mg/1ml accessible in parenteral dosage form. For treating postmenopausal symptoms and osteoporosis you will have to Inject 10 to 20 mg of Progynon Depot intramuscularly at every four weeks. The duration of treatment should not exceed for more than one to five years. For treating prostate cancer you need to inject 30 mg of Progynon Depot, intramuscularly, every 1-2 weeks. Do not exceed more than the recommended dose of Progynon depot. In the case of overdose seek medical help immediately.

What are the contraindications of Progynon depot 10mg/1ml?

  • Do not use Progynon depot in case you are allergic to any of the ingredient present in this medication.
  • If you are suffering from disorders of liver, kidney or heart then using Progynon Depot is inadvisable.
  • If you are suffering from any bleeding disorders, unusual vaginal bleeding or tumors of the pituitary gland then do not use Progynon depot.

What are the probable drug interactions of Progynon depot 10mg/1ml?

  • Antibiotics such as amoxicillin should not be taken with Progynon Depot.
  • Anti-HIV medications such as Ritonavir are prohibited with the use of Progynon Depot.
  • Anti diabetic medications such as Metformin or other hormonal preparations should not be used along with Progynon depot.

What are the possible adverse effects seen with the use of Progynon Depot 10mg/1ml?

Commonly occurring adverse effects seen with the use of Progynon Depot are vaginal itching, weight fluctuations, thinning of hair, breast tenderness, headache, bloating, stomach cramps, and spotting.

What are the safety measures to follow with the use of Progynon depot 10mg/1ml?

  • Do not consume alcohol or smoke while using Progynon depot as it may increase your risk of stroke and blood clotting.
  • Do not overexpose yourself to the sunlight as Progynon Depot makes your skin sensitive to the sun rays.
  • Lactating mothers and pregnant women should never use Progynon depot.
  •  A woman who has not yet undergone menopause or is below the age of 18 years should never use Progynon depot. 

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